Sporanox - antifungal preparation of a wide spectrum of action. It is active against dermatophytes, yeast, yeast-like and mold fungi, causative agents of endemic mycoses. Accepted with onychomycosis, dermatomycosis, genital candidiasis, candidiasis of the oropharyngeal region, with systemic aspergillosis, candidiasis, histoplasmosis and blastomycosis.
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Sporanox product description
Antifungal drug Sporanox is created for the treatment of infectious diseases, provoked by fungal organisms. The mechanism of its action is to suppress the educational process of ergosterols - substances without which the development of fungal organisms and colonies is impossible. As a result of a shortage of vital compounds, cells cease to develop normally, and the pathogen loses its reproductive capacity. All this contributes to the weakening of its functions, and then - the death of the microorganism.
Sporanox is used to fight such diseases:
• Multicolored lichen;
• Mycological lesions of the oral mucous membranes;
• Nail injuries caused by dermatophytes or yeast infection;
• Systemic mycosis;
• Brain defeat (cryptococcal meningitis);
• Histoplasmosis (pulmonary disease);
The drug has an antifungal effect after the end of the course for another 14-30 days. Necessary therapeutic concentration in the nail plate is formed after a weekly medication and is stored for half a year. In addition, the drug penetrates the sweat and sebaceous glands.
Sporanox safety information
The activity and level of the intensity of the effect of the substance depend on the conditions of administration: varies depending on when the medicine was consumed - after eating or on an empty stomach. Therefore, in order to achieve the maximum effect, it is recommended to take capsules after a meal - in this case, peak plasma concentration is formed after 3-4 hours.
Sporanox is not used in the treatment of pregnant women. It can be appointed only in extreme cases - if the condition threatens life. Feeding women should stop lactation at the time of taking a drug because the active substance of the drug penetrates into milk and can be transmitted to the child.
Women of childbearing age are advised to take effective contraceptives in order to prevent conception. They are drinking throughout the course of therapy, and after its completion - before the onset of the lunar period.
Sporanox cannot be used for therapy in the following cases:
• With individual hypersensitivity to component components4
• If the patient undergoes treatment with CYP3A4, Midazolam, Triazolam, Eletriptan, Nisoldipine, HES;
• If the patient suffers from chronic, heart failure;
• In the case of congenital intolerance to fructose, lack of sucrose in the body, malabsorption of glucose-galactose;
• Children 3 years old;
• During pregnancy and lactation.
In the treatment of Sporanox, it must be taken into account that the drug may cause dizziness and other side effects that affect the reaction rate and concentration of attention. People working on vehicles or managing complex mechanisms should consider this.
Patients with low immunity, HIV or those who have undergone an organ transplant operation may need a daily dose correction (increase).
In the treatment of Sporanox, one must take into account that he does not have a certain antidote, and hemodialysis does not help. If a large number of drugs have been taken, it is necessary to rinse the affected stomach as soon as possible - preferably within an hour after ingestion, to give a sorbent. If the condition does not improve, then the treatment is given depending on the symptoms of the condition.
Sporanox side effects
During therapy with Sporanox, undesirable effects can occur in the form of:
• Disorders of the digestive tract (nausea, pain, vomiting, diarrhea/constipation, appetite loss), digestive problems;
• Increase in liver enzymes (is reversible);
• Liver damage (very rarely - with a fatal outcome);
• Allergic reactions;
• A headache, dizziness;
• Skin reactions (rash, itching, urticaria);
• Imperceptibility of bright light;
• Loss of hair;
• Feeling swollen;
• Violation of the heart.
In women, Sporanox therapy can change the menstrual cycle, in men, it reduces potency and affects libido.